The care of burn injuries requires specialist care.  Burn patients represent a unique patient group from the point of view of infection prevention and control (IPC). A burn patient with a severe burn injury is immunocompromised. Severe burn injuries have a significant impact on both the innate immune system and the adaptive immune system. The risk of infection is further increased by invasive devices required for the management of severe burn injuries, such as intravascular catheters and endotracheal tubes. As well as the risk of infection from the burn injury, burn wounds can become heavily colonised with a wide range of microorganisms, including multidrug resistant organisms. These may be dispersed in the healthcare environment and result in outbreaks which may spread to other burn patients and to patient groups. The physical design and layout of burn services aims to minimise the spread of microorganisms between burn patients and to other patients outside the burn service.  There are no guidelines which focus on IPC in burn services and which include the design of the environment. The quality of evidence from studies on IPC in burn patients is generally low. Study design is limited by there being no standardised definition of sepsis burn patients. Key areas of focus specifically for for IPC in burns services include decontamination of the environment, water safety and specialised ventilation.